This eLearning course will discuss recruitment and retention of patient volunteers within a clinical trial. Patient enrollment into active clinical trials has always been challenging. Recruiting a patient into a clinical trial can prove to be difficult. Retaining a patient for the duration of the trial can be even more challenging. With few evidenced-based resources on recruiting styles, the focus of recruitment and retention in this online training course will be limited to the discussion of ethical and regulatory guidelines for the clinical investigator.